Photo by Armando Orlando

Spa Hotels & Resorts in Agnone

  • Plan, book, stay with confidence
    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Best Agnone Spa Hotels

Masseria Acquasalsa
Exterior
Masseria Acquasalsa
9.4 out of 10, Exceptional, (6)
"We stayed Masseria Acqusalsa for 1 night while making our way from Rome to Termoli. It was absolutely amazing. This farmhouse B&B was exactly what we needed after a long flight from the US to rest and enjoy the Italian countryside. The hosts were friendly and beyond accommodating. They made a lovely dinner recommendation to a wonderful restaurant in Agnone and served a fantastic spread for breakfast in the morning. I would highly recommend staying there. "
Masseria Acquasalsa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Agnone
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
Unlock Black Friday deals

Frequently asked questions

Looking for a spa hotel in Agnone?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Enjoy the historical sites and restaurants in Agnone—your day trip starts here. Make sure you pay a visit to the museums during your stay. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Agnone?
Il Duca del Sannio is a top spa hotel featuring a bar and a restaurant. Spend an afternoon at the spa where you’ll find body treatments.
How many spa hotels are there in Agnone?
Among Expedia’s 17 accommodation options in Agnone, there are 2 spa hotels.
What's there to see and do in Agnone?
Experience Agnone with a stop at Marinelli Bell Foundry Museum, Piazza del Plebiscito and Agnone Piazza Vittoria Monumento Ai Caduti. If you have spare time during your trip, you might want to make a stop at Natural Pool of Villa Santa Maria and Bomba Lake.
What is a Agnone spa hotel?
Spa hotels in Agnone feature full on-site spas which offer services such as facials and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on holiday.