All hotels in Southern Illinois, Illinois
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
All hotels in Southern Illinois, Illinois
We have found 974 Southern Illinois Hotels
- Staybridge Suites St Louis - Westport, an IHG Hotel
- Drury Inn & Suites St. Louis Arnold
- The Great Rivers, Ascend Hotel Collection
- Embassy Suites by Hilton St. Louis Airport
- Best Western Plus Parkway Hotel
- Silo Farm Haus- located in the heart of wine country!
- Mustang Inn
- Marriott St. Louis West
- Drury Inn & Suites Sikeston, MO
- Days Inn by Wyndham Paducah
- Guest Host Motel
- Aviator Hotel & Suites South I-55, BW Signature Collection
- Travelodge by Wyndham Terre Haute
- Cozy, Fun, and One-Of-A-Kind!
- Baymont by Wyndham Litchfield
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Super 8 by Wyndham Terre Haute
- Welcome Suites Hazelwood
- Comfort Inn Alton near I-255
- Hampton Inn Cape Girardeau I 55 East
- Holiday Inn Express Vincennes, an IHG Hotel
- Hampton Inn Princeton
- Hampton Inn Terre Haute
- New Harmony Inn Resort and Conference Center
- Comfort Suites
- SpringHill Suites by Marriott Terre Haute
- Red Roof Inn Paducah
- Benton Park Inn
- Americas Best Value Inn St. Louis Downtown
- Hampton Inn Paris
- Super 8 by Wyndham Tuscola
- OYO Hotel St. Louis Downtown City Center MO
- Hampton Inn St. Louis Southwest
- TownePlace Suites by Marriott Vincennes
- Hampton Inn by Hilton Litchfield
- Super 8 by Wyndham Vincennes
- Hampton Inn Vincennes
- Days Inn by Wyndham Sullivan
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.