Florence Cheap Car Rentals & Car Hire Deals

Compare rent a car rates in Florence from popular car rental companies

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

Members save 10% more on select hotels, cars, activities and holiday rentals. Sign up.Opens in a new window

Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

Explore Florence with Cheap Car Rentals and Car Hire Deals

* Price found within the past 60 days. Click for updated prices.

Economy

Chevrolet Spark or similar
  • 4 people
Florence, South Carolina, USA
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Florence, South Carolina, USA
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Florence, South Carolina, USA
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Florence, South Carolina, USA
Jeep Compass
SUV Jeep Compass

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Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
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Frequently asked questions

Can I rent a car from Florence Regional Airport (FLO)?
Florence Regional Airport (FLO) has plenty of choice just a short commute away. Take your pick of vehicles from National Car Rental, Hertz, Avis, Budget or Alamo.
What happens if I need to cancel my Florence car reservation?
If you need to switch your plans around, the majority of prepaid reservations are eligible for a complete refund. Just notify us at least six hours ahead of the scheduled collection time. Read through the policy for any exclusions. Your confirmation will have more details, or jump onto our Customer Service Portal for more info.
Why should I rent a Florence car with Expedia?
From member exclusive discounts to our popular vacation packages, there are loads of reasons to book your next car with Expedia. Headed to Florence? There are suppliers to choose from, with lots of vehicles to suit every budget and style. If you’re eager to save more, combine your rental car with your flights and hotel. Ready to get behind the wheel? We’re ready to get you on your way.
How do I find the best car rental deals in Florence with Expedia?
Whatever type of wheels you’re after, Expedia will help you pick up the best deal. Simply compare offers from leading rental providers and select the option that’s perfect for you. Love to drive away with even bigger savings? Combine your Florence car rental with flight or hotel bookings.
What do you need to rent a car in Florence?
Before you can hop behind the wheel in Florence, you’ll need a driver’s license and a credit card that matches the name on your license. If you decline to take out the rental company’s insurance policy, you may also have to provide proof of alternative coverage. Requirements can vary, so read the policy terms and conditions before you select a rental company.
Can I rent a car for a month or longer in Florence?
Yes, so you won’t have to rebook a rental vehicle mid-vacation. Visit our long-term car rental deals page, enter your information and reserve a set of wheels that’s all yours for the duration of your getaway.
Where can I find a Florence car rental if I am younger than 25?
This will depend on the rental companies that are in Florence. They often have different age policies. If you’ve found a place that does cater to drivers under 25 be aware that extra costs may apply. Conduct some research into what those charges could be before booking your rental.